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This process, using glutamate (Glu), cysteine (Cys), and glycine (Gly) as raw materials, depends on glutamate cysteine ligase (GCL) and glutathione synthetase (GS) catalysis, present only in the cytoplasmic matrix [23]

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NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation