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Other Risk Factors : People with chronic alcoholism, those taking certain medications (like metformin or proton pump inhibitors), or individuals with specific genetic mutations affecting B12 metabolism may also benefit from B12 injections

In most cases, multiple weekly injections are considered to be beneficial in achieving a weight loss target

ClinicalTrials.gov lists 3 ongoing or completed trials (accessed February 12, 2026): NCT05239615 (topical for photoaging, Phase II, completed 2024, no results posted) [12]

Side effects are uncommon and typically limited to mild injection site reactions

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Environ Sci Process Impacts 18:7886