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Glutathione is a powerful antioxidant naturally produced in our cells

It also upregulates the transcription of IL-1, IL-18, and TNF-, forming positive feedback

doi: 10.1016/j.ecoenv.2021.112754 31

To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

EBV in particular has been implicated as a trigger for multiple autoimmune conditions, including lupus, MS, and rheumatoid arthritis

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