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In a randomized clinical trial published in JAMA Psychiatry, semaglutide reduced alcohol craving and improved some drinking outcomes versus placebo in adults with alcohol use disorder

The biggest takeaway from clinical trials is that side effects are dose-related and almost always show up during dose increases

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For instance, central pathways governing feeding and metabolism start to develop at specific stages of early life and, at this time, the animal is particularly vulnerable to influences from the environment