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One limitation of the feedback control system used here for potential application in biomanufacturing is its use for a natural product regulated by feedback inhibition

However, initial results have produced significant reductions in body weight and many other benefits

Pancreatitis can cause severe abdominal pain and may require hospitalization

Heart rate may increase slightly in some individuals, though this is typically modest and resolves with time

While the concept is clinically intriguing, establishing an evidence base through well-designed studies will be essential before broader adoption can be considered

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