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Furthermore, the microcapsules effectively enhanced the activity and gene expression of antioxidant enzymes, suggesting improved antioxidant status

SULT1A1 is believed to be the major enzyme associated with paracetamol sulphation, although SULT1A3/4 and SULT1E1 have also been implicated in the foetus and neonates [20, 35, 36]

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Furthermore, in a post hoc analysis of the cagrilintide monotherapy arm in REDEFINE 1, cagrilintide led to clinically meaningful reductions in body weight and waist circumference versus placebo and presented a favourable safety profile [11]

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