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That means there is no approved pharmaceutical version available through pharmacies, and the compound cannot be prescribed by physicians

Esposito, Feasibility of simplification from a basal-bolus insulin regimen to a fixed-ratio formulation of basal insulin plus a GLP-1RA or to basal insulin plus an SGLT2 inhibitor: BEYOND, a randomized, pragmatic trial

Most side effects are worst during dose escalation

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