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Upon delivery of Epithalon, it was observed that the incidence of the chromosomal aberrations in the bone marrow of SAMP-1 mice with accelerated aging appeared to be almost 2 times higher than the other two models

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By the negative crosstalk between WNT and PPAR, lithium administration, by inhibiting the GSK-3 could act as a PPAR antagonist and lead to an increase in the WNT pathway, resulting in diminution of oxidative stress

J Phar Sci 111(4):426432