tirzepatide vs semaglutide trial In the SURMOUNT-5 phase 3b involving adults with obesity without type 2 diabetes, was superior to in reducing body weight and waist circumference. Full trial results and Research Summary Everyone's picking a side. 💛🆚💙

It has all the same GI side effects as other GLP-1 medications, plus a few unique ones like dysesthesia

Many of the studies confirming CV and renal benefits of SGLT2 inhibitors and GLP-1s were published after 2020

A separate analysis of the STEP 1 data found that lean mass was reduced by 6.92 kg with a total weight reduction of 15.3 kg, meaning roughly 45 percent of the weight lost was lean mass

For example, akin to GLP-1R-expressing vagal afferents, wingless-related integration site 1 (WNT1)-expressing spinal afferents densely innervate the muscular wall of the ileum and large intestine [37]

14 Low B12 and/or low folate are both risk factors for high homocysteine, which is common in people with MTHFR mutations

this disrupts the bacterias ability to make proteins necessary for its growth and survival