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A practical, layered approach includes: Hydration: Aim for 6480 ounces of water daily

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Carnitine facilitates the transport of long-chain fatty acids into the mitochondria, known as the carnitine shuttle, which involves three enzymes: carnitine palmitoyltransferase 1 (CPT1) for forming acylcarnitines in the outer mitochondrial membrane, carnitine-acylcarnitine translocase (CACT) for shuttling acylcarnitine across the inner membrane, and carnitine palmitoyltransferase 2 (CPT2) for liberating free fatty acids for -oxidation in the mitochondrial matrix ( 7 )