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This is not necessarily a negative side effect but rather an indication of accelerated cell turnover, where underlying congestion is brought to the surface as the skin rapidly sheds old cells and regenerates new ones

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Motor functioning was evaluated starting at 2 weeks post-surgery and testing was conducted on a biweekly basis using a walking track analysis where the rats were made to walk in a confined walkway lined with white paper and led into a dark shelter

348 While SERMs regulate ER activity instead of inhibiting it, promising results have been observed with lasofoxifene, a new-generation non-steroidal SERMs

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For instance, pathogenic bacteria often express specific surface proteins, LPS, or carbohydrates that are absent in beneficial microbiota