When fat is broken down, it is processed through the liver to be used as energy or eliminated
SGLT2 inhibitors, such as empagliflozin and canagliflozin, have similar A1C-lowering properties (0.5%-0.8%) and out-of-pocket costs (except for alogliptin, which is available generically), but have the added advantages of CV risk reduction, BP-lowering, and weight loss
Effect of L-carnitine on exercise tolerance in patients with chronic stable angina pectoris
Nevertheless, understanding GI adverse events across both earlier and newer GLP-1based therapies remains highly relevant, particularly as these agents are increasingly prescribed for long-term and off-label indications
Mechanism, efficacy, and when to use each
Muallem MM, Rubeiz NG