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Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

doi: 10.2337/db24-1668-P

The difference can be very meaningfulseveral percentage points higher for the Rx trend. In some cases, overall prescription drug trend may jump by as much as 15% when GLP-1 medications are included, making them a dominant contributor to pharmacy cost growth

Some compounded formulations already include B12, like semaglutide with B12 and tirzepatide with B12 , which simplifies the supplementation process

75% of patients who initiate a diabetes-indicated GLP-1 have filled metformin or another diabetes treatment prior to initiation, while the majority of weight-loss indicated GLP-1 initiators have had no prior fills of any diabetes products

2023 Apr;33(3):159-166