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Degeneration of the lower motor neurons in the brainstem and spinal cord and the upper motor neurons in the motor cortex results in gradual denervation of voluntary muscles, leading to disruption of neural networks through a complex set of mechanisms eventually culminating in motor and non-motor symptoms (28)

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Compounded drugs are not FDA-approved, leading to concerns over safety and efficacy

Up-regulation of glutamate receptors is associated with LTP defects in the early stages of diabetes mellitus

A biopsy of the left sural nerve and left gastrocnemius muscle demonstrated severe axonal neuropathy (Fig

Because the ingredients are legend-only at these concentrations, the cream must be prescribed by a licensed clinician, dispensed for an identified individual, and labeled with beyond-use dating that reflects USP guidelines