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Patil and Mitra (2026) highlight this in their report on Addison's disease - a condition of adrenal insufficiency where the body produces excess adrenocorticotropic hormone (ACTH), which in turn stimulates melanocytes throughout the body, including in oral mucosa

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Persistent oxidative stress is closely related to the delayed healing of diabetic wounds, and lipid peroxide accumulation via the circulation further contributes to iron metabolic pathway disruption

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While there is a growing body of evidence supporting the neuroprotective properties of UA, gaps persist in understanding the underlying mechanisms that drive its beneficial effects