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8.1.1 Genomic and system-level approaches In the last two to three decades, NGS technologies have generated large amounts of omics data (genomics, transcriptomics, proteomics, epigenomics, and metabolomics), post-translational modification data (phosphorylation, SUMOylation, ubiquitinylation, etc.), single-cell, ATAC-Seq data and more, which provide a powerful lens for deciphering the molecular landscape of breast cancer (269)