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The mean daily insulin dose at baseline was 53 units in patients treated with saxagliptin 5 mg and 55 units in patients treated with placebo

To date, two incretin hormones have been discovered: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) [2]

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PMID: 30850040

Another animal study reported that liposome-encapsulated p-coumaric acid (CA) inhibited osteoclast formation and bone resorption in a rat model of rheumatoid arthritis, suggesting its potential to prevent bone degradation and calcium loss (140)