As a commonly used clinic chemotherapeutic agent, cisplatin resistance in cancer is associated with the decreased intracellular drug accumulation, and the enhanced DNA repair capacity along with dysregulation of ferroptosis-related signaling pathways
Blockade of GLP-1R with exendin-(939) antagonized the antiapoptotic actions of exendin-4
For example, people with liver or kidney disease or who are overweight or obese are known to have a carnitine deficiency or lower levels than otherwise healthy people
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Certain peptides interact directly with melanocortin receptors in the brain