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Yet, in specific experiments, non-androgenized control animals, included for reference purposes, were fed a standard chow diet, with a dry matter composition of 3.5% fat, 5.9% fiber, 14% proteins, and 57.5% water-soluble carbohydrates, estimated as N-free-extracts (LASQdiet, Rod14-R)

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Metformin is the preferred initial pharmacologic agent for treating type 2 diabetes mellitus (T2DM), and other glucose-lowering agents can be considered according to comorbidities or patient-centered treatment factors [4,5]

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