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In 2025, the American Association of Clinical Endocrinology updated its Obesity Algorithm, which highlights the importance of preserving skeletal muscle during medical weight-loss interventions: patients who retain strength tend to experience fewer side effects, more energy, and better long-term weight maintenance

It's about biology

Left, cAMP response taken 25 min after ligand addition

Propensity-score matching Due to imbalances in sex, age at baseline, and inclusion date, we matched the two groups on propensity scores estimated from these variables

But he was actually the first one, I think to say if GLP-1 has all of these important effects in the pancreas and to protect cells, and there are all these GLP-1 receptors in the brain, maybe it also protects neurons

GLP-1s are everywhere