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Data normality was assessed by the Shapiro-Wilk test, and appropriate tests were chosen according to data distribution
dose reduction is described when IGF-1 exceeds the lab's upper reference range
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Inclusion criteria selected for patients with a diagnosis of epilepsy, an average of at least 2 seizures per month over the preceding 3 months prior to starting MAD, at least 18 years of age at the time of enrollment, having baseline carnitine lab measurement prior to starting MAD, and at least one carnitine lab measurement at a follow-up timepoint
The l arginine vs citrulline market positioning reflects price sensitivity considerations, with l-arginine offering cost advantages for mass-market products and l-citrulline commanding premium positioning in performance-focused applications targeting educated consumers.
The answers below summarize what researchers and regulators know so far based on current clinical trials and public data
