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There is much debate surrounding the tolerability of an increased risk of DKA, with comparisons being made with troglitazone and its subsequent removal from the market where the risk of fatal liver failure was greater than the current risk of DKA with SGLT2i use [31]

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Individuals with higher incomes and under age 55 were less likely to stop the medications, and those with obesity were more likely

MEDI4166 is fully stable in cynomolgus monkey for at least 9 days following intravenous administration with no discordance between Fc and GLP-1R active compound concentrations

Diabetes 60 , 23972406 (2011)