Likewise, reduced dehydroascorbic acid (an oxidized form of ascorbic acid) combined with increased threonic acid (a major breakdown product of ascorbic acid) levels in the CSF indicates a change in oxidative stress response: dehydroascorbic acid has neuroprotective effects against free radicals in the brain, while threonic acid may interfere with the metabolism of ascorbic acid [137]
L-Carnitine's role in PCOS involves improving metabolic functions
GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) mimic this hormone to slow gastric emptying, reducing appetite and curbing food cravings
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when mitochondria have extensive and severe damage, excessively activated mitophagy will further exacerbate cellular energy crisis and functional failure
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