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Beyond its direct impact on insulin, GLP-1 also suppresses glucagon secretion, slows gastric emptying, and promotes satiety by acting on appetite control centers in the brain, all of which contribute to improved glycemic control and reduced caloric intake, leading to weight loss (Ard, Jamy et al

76 Exenatide is composed of 39 amino acids and shares 53% sequence identity to human GLP-1

Foods that contain good-for-you unsaturated fats, however, may actually increase GLP-1 secretion, making the medication more effective

YZ participated in topic design, manuscript writing, manuscript editing and providing instructional support

Patients will maintain the standard 0.25mg dose for the first four weeks before increasing to 0.5mg in the fifth week, followed by 1mg for the subsequent increase

Mentero, et al