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Weight-bearing exercise (walking, jogging or any exercise done on the feet) and strength training for muscles can help fortify bones and build bone mass
In fact, mice with hepatocyte-specific DPP-4 knockdown have a significant reduction in serum DPP-4 activity and reduced adipose tissue inflammation, insulin resistance, and glucose intolerance [20]
They are most valuable for patients who are already committed to lifestyle changes but need additional support to see consistent results
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That said, real-world results may vary depending on your sleep habits, stress levels, and overall health