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Clinical Evidence and Current Research Gaps No randomised controlled trial has tested glutathione supplementation specifically in patients on GLP-1 or dual-agonist medications

All procedures and methods were conducted in accordance Declaration of Helsinki 10

Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, which typically diminish over time

Multidrug-resistant proteins, which are commonly upregulated in cancers, can also transport GSH (114)

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This improved sensitivity works synergistically with Retatrutides direct effects on insulin secretion and action