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The PI3K/Akt axis activated by IGF1R is protective against ischemic injury in cardiac models, and LR3 has been used as a tool in cardioprotection studies, often in conjunction with other research compounds for combined mechanism investigation

Separate vials are only advantageous for dose-titration studies where researchers need independent control of each peptides dose

doi: 10.1016/S0140-6736(05)17987-2

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This increased bio-availability allows research teams to explore extended cellular signaling events without the rapid degradation typically observed with standard IGF-1

Test subjects were divided into two groups