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We quantified the Euclidean distance between this optimal target coordinate and the actual target coordinate, which was determined by the centre of gravity of each patients lesion

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Establish progression rate if pre-existing disease (reviewing old records showing change over time)

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10.3390/membranes13020193 65 MiaoZ.ZhangL.GuM.HuangJ.WangX.YanJ.et al (2021)