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Therefore, we conducted a thorough characterization of the chondrocyte phenotype and demonstrated that cells at P6, although exhibiting reduced levels of COL2 compared to P3, still produce considerable levels of this protein relative to a fibroblastic negative control

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This is due to its basis on Michaelis-menten and first order kinetics which are closely associated with the catalytic reaction mechanism of enzymes (Boeckx et al., 2017)

Oesophagogastroduodenoscopy ( OGD , gastroscopy) is the investigation of choice for upper GI disorders with the possibility of therapy and mucosal biopsy