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Who Might Consider BPC-157 and Who Should Avoid It Based on the preclinical data and clinical patterns of use, the patient populations most commonly prescribed BPC-157 for GI indications include: patients with persistent NSAID gastropathy despite PPI therapy, patients with functional GI symptoms attributed to intestinal barrier dysfunction, and patients with inflammatory bowel disease who have not responded adequately to biologic therapy and seek adjunctive options

Docusate is widely used, but clinical trials have not demonstrated meaningful benefit over placebo and it is less effective than fiber or osmotic laxatives

SGLT2i were initially approved for the treatment of type 2 diabetes in 2013 due to their glucose lowering effects

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