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However, as expression of IGF-IEa peaks later than M-cadherin[19], MGF may be the initial IGF-I isoform that triggers the activation of SCs, followed by the later expression of IGF-IEa to maintain protein synthesis[19]

Moreover, resveratrol enhances granulosa cell mitochondrial function and energy metabolism by activating the SIRT1/PGC-1 pathway [109]

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The second way it does this is by actually increasing the number of blood vessels

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