Mol Cancer Ther (2017)
High GGT levels may suggest liver damage, which can result from alcohol abuse, certain medications, fatty liver disease, hepatitis, or bile duct blockage
3328-A THE HIGHER RISK OF LIVER CIRRHOSIS IN PI*MZ SERPINA1 CARRIERS IS NOT CAUSED BY THE PRESENCE OF A DIFFERENT PRECIPITATING MUTATION Sona Frankova 1 , Zuzana Rabekova 2 , Magdalena Nerolodova 2 , Ondrej Fabian 2 , Martin Kveton 2 , Milan Jirsa 2 and Jan Sperl 1 , (1)Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, (2)Institute for Clinical and Experimental Medicine Background: The homozygous carriage of the mutated Z allele at the rs28929474 locus in the SERPINA1 alpha-1-antitrypsin (AAT) gene leads to pulmonary emphysema and liver cirrhosis
BioFactors 8:1721 Salehi B, Berkay Yilmaz Y, Antika G, BoyunegmezTumer T, FawziMahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N, Cho WC, Sharifi-Rad J (2019) Insights on the use of alpha-lipoic acid for therapeutic purposes
18th Oncology Update Advances and Controversies
While this could indicate that flux through the PPP is necessary to compensate for oxidative processes downstream of glycolysis, it is also possible that optimal PPP flux is needed during the initial steps of activation