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Mistake: Dosing MOTS-c orally expecting high bioavailability

DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide first isolated from rabbit cerebral venous blood, studied in neuroregulatory and sleep architecture research models since the 1970s

However, Hinge did effectively inhibit spine formation in neurons stimulated with 10 ng/ml HGF (Figure 13B), 10 " 12 M Nlel-AnglV ( Figure 13C) or lO "12 M Dihexa ( Figure 12D) further supporting the contention that these actions are mediated by the HGF/c- Met system

10.1007/s11051-023-05806-2 188

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