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For instance, oxidized AAT inhibits inflammation in response to cigarette smoke in vivo 155 and induces a broad anti-inflammatory profile in gene expression of primary human lung microvascular endothelial cells

Gastroenterology 101 :540547

J Gastroenterol Hepatol (2023) 38:133345

[DOI] [PubMed] [Google Scholar] 32.Leung PY, Miyashita K, Young M, Tsao CS

Melatonin has been reported to bind KEAP1, thereby disrupting this interaction and permitting NRF2 to translocate to the nucleus where it can activate antioxidant response element (ARE)-driven gene expression (41, 62, 63)

65 However, an observational study that followed 501 couples attempting pregnancy for 12 months found neither mens daytime nor nighttime underwear choice had an impact on time to conception or risk of infertility