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Moreover, the steric condition is not hindered in this step for the cysteine, which can easily interact with the oxygen atom of the coordinated OOH group

Kashiwagi, Catalysts 8 , 649 (2018) V.A

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For growth hormone deficiency , NICE has appraised the use of licensed recombinant human growth hormone (somatropin) in adults and children, with eligibility subject to defined clinical criteria