Opportunities and challenges following approval of resmetirom for MASH liver disease
Understanding your health profile helps healthcare providers tailor treatment plans
Example dosage schedule Starting dose: 0.2 0.3 mg weekly for first 4-5 weeks Titration phase: 0.4 0.6 mg weekly for 4-5 weeks and then, if tolerated, 0.9 1.1 mg weekly for 4-5 weeks Maintenance dose for long-term weight management: 1.6 1.9 mg weekly for 4-5 weeks and then, if tolerated, 2.5 mg weekly (maximum dose) The dosage may vary depending on the individual needs, your initial BMI, and glycemic control
Upon FDA approval, the Ozempic warning label states that semaglutide may cause harm to the fetus and that women should stop the diabetes drug at least two months before planning a pregnancy
However, NHS access, safety and monitoring remain central
"We also wish the study had continued longer in order to have more statistical power for some of the secondary outcomes and subgroup analyses." Despite these limitations, Ms Raffoul and Dr Tang agreed the analysis was a sound study which contributed further evidence about potential benefit of semaglutide to high-risk populations