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J Can Dent Assoc 2004;70:6823

[11] Additionally, Rich suggested avoiding choline or TMG supplementation, as it could push the BHMT pathway at the expense of the methionine pathway, and to avoid over-supplementing with different forms of folate that would compete for absorption

It can also result in anorectal malformations which can affect the development of the enteric nervous system (27)

But its not the whole story

However, some studies indicate a possible association with: If you experience severe side effects, contact a healthcare provider immediately

Material and methods: The studies were conducted on laboratory animals, in this case male and female albino rats