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November 29, 2012

D.Shojaei-ZarghaniS.TaherifardE.DastghaibS.ParsaS.MohammadiN.et al (2023)

Both groups showed similar improvements in HbA1c and insulin sensitivity, but the pioglitazone group additionally showed increased levels of mitochondrial gene expression and AMPK phosphorylation [124]

In a rat model of Parkinsons disease (PD) induced by 6-hydroxydopamine (6-OHDA), the systemic administration of the antibody significantly mitigated the degeneration of dopaminergic neurons through the suppression of neuroinflammation, the reduction of ROS generation, and the preservation of BBB integrity [356]

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397 Despite these promising results, safety concerns remain a major hurdle for VERVE-101