For now, he says, the jury is out on whether GLP-1s could offer any athletic advantage
It was approved for the treatment of type 2 diabetes in the United States in May 2022, and for the management of obesity in November 2023
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As more patients take these drugs, we are finding more about their benefits and drawbacks
For context, NICE guidance on existing approved GLP-1 receptor agonists for example, NICE TA875 (Semaglutide for managing overweight and obesity, 2023) acknowledges GI side effects as a recognised class effect and supports gradual dose escalation to improve tolerability
The FDA responded by agreeing to allow compounding pharmacies to continue producing off-label versions of tirzepatride while it re-evaluates the situation