doi: 10.1016/j.psychres.2018.04.029 Summary Keywords lipid dysregulation, depression, neuroinflammation, insulin resistance, leptin, adiponectin, mitochondrial dysfunction, endoplasmic reticulum stress Citation Ge Z, Hu Y, Kan W, Li L, Xu J, Zhang Y, Zheng N, Wang G and Du J (2025) Lipid metabolic dysregulation-induced neuroinflammation in the pathophysiology of major depressive disorder
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Compounded tirzepatide at Vesta is the same dual GLP-1/GIP receptor agonist, prescribed for medical weight loss with provider-led titration
It is extensively studied in preclinical models for its ability to promote dendritic spine formation, enhance synaptic plasticity, and support neuronal regeneration
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For the single-site ELISA, also designed to measure total GLP-1, we used a newly developed customised xMAP-based assay (catalogue no