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LPL is synthesized in the adipose and oxidative tissues and is packaged into secretory vesicles using either a sphingomyelin-specific pathway with heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) or a bulk flow secretion pathway 3

Both medication classes can cause digestive symptoms, and concurrent use may intensify these effects in some individuals

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Lancet Diabetes Endocrinol 2019;7:344-55.ArticlePubMed 276

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