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Taking a massive single dose of berberine is not only ineffective due to absorption limits but is also highly likely to cause significant gastrointestinal distress, including cramping, diarrhea, and bloating

10.1158/0008-5472.Can-13-3058 [DOI] [PMC free article] [PubMed] [Google Scholar] Corradin G., Kajava A

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[] Statistical analysis Results were statistically analyzed using the mini-tab statistical program

It is studied for its roles in sleep and stress-related signaling

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