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Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models

For kinetic CYP3A4 activation and inhibition testing, ketoconazole or rifampicin (MilliporeSigma, catalog: R7382) was prepared at 2 final concentration in culture medium containing 2 luminogenic CYP substrate

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Many of the beneficial effects of DHA may be through the expression of BDNF

doi: 10.1111/j.1582-4934.2004.tb00275.x