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Exclusion Criteria: * Myocardial infarction, stroke, hospitalization for unstable angina pectoris or transient ischaemic attack within 180 days prior to the day of screening

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doi: 10.1038/s41598-021-02375-z, 26 KostyakJ

Hyperandrogenism accompanies increased intra-abdominal fat storage in normal weight polycystic ovary syndrome women

Escalation protocol with weekly or biweekly titration

For most enzyme inducers, hyperplasia is transient and may require specific DNA labeling studies or immunohistochemical stains to clearly identify its occurrence