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10.1002/mame.201700660 9 CirilloG.Gianfranco SpizzirriU.CurcioM.HampelS.VittorioO.RestucciaD.et al (2016)

CrossRef An in vitro model to study molecular pathogenesis of sarcopenia established by a SASP-dependent human myotube culture Kiyo-aki Ishii, Ryo Hashimoto, Chikako Umeda, Tohru Hosoyama, Ken Watanabe, Keisuke Hitachi PLOS One.2025

In humans, glutamine is synthesized from glutamic acid and this conversion step is vitally important in regulating the level of toxic ammonia in the body, forming urea and purines

Furthermore, the levels of GSH decreased with increased oxidative stress markers in the HFD-fed mice, which reflect the exhaustion of antioxidant potential and increased oxidative stress

10, 2009, pp