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Their release of histamine, tryptase, and matrix metalloproteinases (e.g., MMP9) contributes to blood-brain barrier breakdown and promotes infiltration of autoreactive T cells

Pagnamenta AT, Wing K, Sadighi Akha E, Knight SJL, Blte S, Schmtzer G, Duketis E, Poustka F, Klauck SM, Poustka A, Ragoussis J, Bailey AJ, Monaco AP, (IMGSAC) and the IMGS of AC (2009) A 15q13.3 microdeletion segregating with autism

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Within these constraints, McGowan et al

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