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Finally, BPC 157 has a considerable potential to counteract thiopental anesthesia (i.e., BPC 157 in doses of 10 ng/kg and 10 g/kg, respectively, caused significant counteraction of loss of righting reflex produced by thiopental with a parallel shift of the doseresponse curve for thiopental to the right) [218]

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Two primary reasons: First, immunogenicity