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Description

3,28 One approach is to prevent degradation by DPP-IV through amino acid substitutions, as this enzyme preferentially cleaves N-terminal Xaa-Pro or Xaa-Ala sequences

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doi: 10.1097/GCO.0000000000000548 74 LaverySGillmerM

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Collectively, these velocity-based methods provide accurate, non-invasive, and efficient drug administration, especially advantageous for macromolecules and formulations exhibiting low passive permeability

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