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To achieve this, we employed Lipid Nanoparticles (LNPs), which have components similar to Patisiran, a clinically approved product known for effective hepatic transfection 23,24

The antigens are associated to MHC II molecule that interacts with T-cell receptor of T CD4 + lymphocytes, leading the antigen recognition and, subsequently, activation

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Results Post hoc analysis by gender Among 3297 subjects in the SUSTAIN 6 study population, 2002 were male and 1295 were female (Table 1A)