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Early worsening of diabetic retinopathy in individuals with type 2 diabetes treated with tirzepatide: a real-world cohort study

Patients often exhibit structurally abnormal, swollen mitochondria with disrupted cristae, impaired mitochondrial recycling (a process called mitophagy), and chronically elevated levels of reactive oxygen species

However, the drugs can be costly, difficult to find and to have some side effects, such as gastrointestinal issues

Daskalakis NP, Bagot RC, Parker KJ, Vinkers CH, de Kloet ER

Once GHRH is in play, it beckons the pituitary gland to release growth hormone